Nocistatin inhibits pregnant rat uterine contractions in vitro: Roles of calcitonin gene-related peptide and calcium-dependent potassium channel

Investigation of the effects of nociceptin and nocistatin on pregnant uterine contractions in vitro

I. Deák Beáta, Klukovits Anna, Kormányos Zsolt, Falkay György, Gáspár Róbert. A nociceptin és nocisztatin hatása a terhes humán és patkány uterusz kontraktilitására. A Magyar Élettani Társaság (MÉT) és a Magyar Kísérletes és Klinikai Farmakológiai Társaság (MFT) II. Közös tudományos konferenciája; Szeged, 2010. június 16-18. II. Beáta H Deák, Anna Klukovits, Eszter Ducza, Zsolt Kormányos, Attil...

Comparison between Brain Natriuretic Peptide and Calcitonin Gene Related Peptide in Children with Dilated Cardiomyopathy

Background: Dilated cardiomyopathy (DCM) is revealed with the left ventricular dilatation and systolic dysfunction. This study was performed to determine the level of Calcitonin Gene Related Peptide (CGRP) and Brain Natriuretic Peptide (BNP) in children with dilated cardiomyopathy and controls and comparison of these two biomarkers in patients. Materials and Methods: This case-control study was...

Roles of calcitonin gene-related peptide in ehancement of angiogenesis

Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide produced by tissue-specific alternative splicing of the primary transcript of the calcitonin/CGRP gene. CGRP is widely distributed in the central and peripheral neuronal systems and exhibits numerous biological activities in mammals. Recently, it was clarified that endogenous CGRP released from primary afferent neurons facil...

Calcitonin gene related peptide.

Cerebroventricular calcitonin gene-related peptide inhibits rat duodenal bicarbonate secretion by release of norepinephrine and vasopressin.

Proximal duodenal bicarbonate secretion is an important factor in humans and animals protecting the mucosa against acid-peptic damage. This study examined the mechanisms responsible for the central nervous system regulation of duodenal bicarbonate secretion by calcitonin gene-related peptide (CGRP) in unrestrained rats. Cerebroventricular administration of rat CGRP significantly inhibited basal...